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FNIH Biomarkers Consortium Plasma Abeta Project: Wash U: 2021-11-05

Source: R/data.R
PLASMA_ABETA_PROJECT_WASH_U.Rd

FNIH Biomarkers Consortium Plasma Abeta Project: Wash U: 2021-11-05 data. More information is available at https://adni.loni.usc.edu/data-samples/adni-data/

Usage

data(PLASMA_ABETA_PROJECT_WASH_U)

Format

A data frame with 130 observations and 29 variables.

Source

https://adni.loni.usc.edu/data-samples/adni-data/

Details

  • ORIGPROT character Original study protocol , with options: ADNI1, ADNIGO, ADNI2

  • RID numeric Participant roster ID Range value: 31, ..., 5263

  • VISCODE character Visit code , with options: v41, v51, init, v52, v21

  • VISCODE2 character Translated visit code

  • EXAMDATE Examination Date Date: YYY-MM-DD

  • GUSPECID character

  • VID numeric Range value: 0, ..., 14

  • DER character , with options: PLA

  • DRAWTIME hms: HH-MM-SS

  • FILE_NAME_NE character

  • LC_MS_SAMPLE_ID character Internal ID of LS_MS sample to control for technical replicates. It serves as internal blinding ID and for QC purpocess

  • SAMPLE_TYPE character Type of LC_MS sample (FNIH Clinical Plasma; FNIH QC; FNIH CSF; QC Calibrator) , with options: FNIH Clinical Plasma

  • INJECTION character injection (technical replicate) 1-st denoted as 'a'; second as 'b' ei. , with options: a, b, c

  • INSTRUMENT character Masspectrometer (Lumos; Altis) , with options: Lumos

  • BATCH character Indicates the batch in which the sample was processed (prepped) for LC-MSMS , with options: FNIH #01, FNIH #03, FNIH #02

  • ASSAY character Experiment file name , with options: 20210125_FNIH-01_hPlasma_Dyna_0^5mL_OTL_NO-HM_VO_VO, 20210208_FNIH-03_hPlasma_Dyna_0^5mL_OTL_NO-HM_VO_SL, 20210201_FNIH-02_hPlasma_Dyna_0^5mL_OTL_NO-HM_VO_AB, 20210129_FNIH-02_hPlasma_Dyna_0^5mL_Altis_NO-HM_VO_JB

  • ASSAY_IP_PROTOCOL character Sample processing protocol , with options: IP: 0.5mL Hamilton/MCX/Oxi Ver 2.0

  • QC_STATUS character Status of samples assign by quality control comitte (Passed; Failed). If failed, samples should not be used for further analysis , with options: Passed, Passed with warnings, FAIL

  • QC_FLAGS character None or one or many QC flags assigned by QC comitte when sample does not meet respective quality criterias , with options: (03) Retention Time; (08) Peak Shape;, (03) Retention Time;, (08) Peak Shape;, (00) No signal

  • QC_COMMENT character Detailed description of QC decision if applicable , with options: Ab40 broad, Ab40

  • MS_RUN_DATE numeric date when sequense get started to run on LC-MSMS Range value: 20210125, ..., 20210208

  • AB40 numeric raw plasma A40 concentration, ng/ml (those are not standardized and should not be used for analysis) Range value: 0.204541, ..., 0.426322

  • AB42 numeric raw plasma A42 concentration, ng/ml (those are not standardized and should not be used for analysis) Range value: 0.0250732, ..., 0.0515734

  • PLASMAAB4240 numeric Concentration ratio of 42/40 as measured by Di-oxidized C-terminal peptides, based on its relation to respective known concentrations of N15 internal standard Range value: 0.10406, ..., 0.159464

  • STANDARDIZED_PLASMAAB42 numeric Standardized plasma A42 concentration, ng/ml Range value: 0.0242431, ..., 0.0512758

  • STANDARDIZED_PLASMAAB40 numeric Standardized plasma A40 concentration, ng/ml Range value: 0.199088, ..., 0.428188

  • STANDARDIZEAB42_STANDARDIZEDAB40 numeric Range value: 0.106584, ..., 0.162097

  • STANDARDIZED_PLASMAAB4240 numeric The standardized_plasmaAB4240 variable should be used for analyses. This value is the measured abeta 42/40 by our lab. Range value: 0.108011, ..., 0.163192

  • update_stamp POSIXct: YYY-MM-DD

Author

adni-data@googlegroups.com