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ATRI clinical analysis dataset.

Usage

data(cdr)

Format

A data frame with 15511 rows and 25 variables.

Details

  • SUBSTUDY: NA

  • BID: NA

  • VISCODE: NA

  • DONE: Was assessment/procedure done?

  • NDREASON: If No, reason not done:

  • CDSPVERS: Version

  • CDPTSRCE: Participant

  • CDSPSRCE: Study Partner

  • BPID: Study Partner ID:

  • MEMORY: Memory Score

  • ORIENT: Orientation Score

  • JUDGE: Judgment and Problem Solving Score

  • COMMUN: Community Affairs Score

  • HOME: Home and Hobbies Score

  • CARE: Personal Care Score

  • CDSOB: Sum of Boxes (system populated)

  • CDGLOBAL: Global CDR (system populated)

  • AVISIT: Analysis visit.

  • CDADTC_DAYS_CONSENT: Analysis date of CDR registry.EXAMDATE, if it exists, otherwise manually reviewed missing_pacc_dates_verify.EXAMDATE.verify (Derived to days since study consent date)

  • CDADTC_DAYS_T0: Analysis date of CDR registry.EXAMDATE, if it exists, otherwise manually reviewed missing_pacc_dates_verify.EXAMDATE.verify (Derived to days since study start date [A4: Ranomization date | LEARN: Baseline registry exam date])

  • EPOCH: Epoch.

  • CDDY: Study day of CDR collection, measured as integer days.

  • CDEVENT: CDR-Global progression event defined as two consecutive CDR-Global scores in the placebo-controlled phase greater than zero, or a final observed CDR-Global score in the placebo-controlled phase greater than zero. The time of the event will be considered the time from baseline (in days) from randomization to the first of two consecutive CDR-Global scores greater than zero, or to final observed CDR-Global score greater than zero. If a participant has only CDR-Global scores of zero at every visit, the censoring time will be the time of the last observed CDR-Global score in the placebo-controlled phase.

  • CDOLEEVENT: OLE CDR-Global progression event defined as two consecutive CDR-Global scores in the placebo-controlled or OLE phase greater than zero, or a final observed CDR-Global score in the placebo-controlled or OLE phase greater than zero. The time of the event will be considered the time from baseline (in days) to the first of two consecutive CDR-Global scores greater than zero, or to final observed CDR-Global score greater than zero. If a participant has only CDR-Global scores of zero at every visit, the censoring time will be the time of the last observed CDR-Global score in either placebo-controlled or OLE phase.

  • CDRSB: CDR Sum of Boxes score with proration for missing box scores if percent missing is <= 30

Examples

if (FALSE) { # \dontrun{
browseVignettes('A4LEARN')
} # }