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ATRI derived analysis dataset.

Usage

data(SUBJINFO)

Format

A data frame with 6945 rows and 64 variables.

Details

  • SUBSTUDY: NA

  • BID: NA

  • TX: Random treatment assigment.

  • AGEYR: Age in years at Consent

  • MARITAL: Marital Status

  • SEX: Sex

  • RACE: Race

  • EDCCNTU: Years of education

  • ETHNIC: Ethnicity

  • WRKRET: Participant Retirement Status

  • TESTLNG: Language to be used for testing

  • SAMELNG: Testing and Primary Lang are the same

  • RESIDENCE: Type of Residence

  • DISCDTC_DAYS_CONSENT: Subject Discontinuation Date Character (Derived to days since study consent date)

  • DISCDTC_DAYS_T0: Subject Discontinuation Date Character (Derived to days since study start date [A4: Ranomization date | LEARN: Baseline registry exam date])

  • ENRLDT_DAYS_CONSENT: Enrollment Date (Derived to days since study consent date)

  • ENRLDT_DAYS_T0: Enrollment Date (Derived to days since study start date [A4: Ranomization date | LEARN: Baseline registry exam date])

  • RNDMDT_DAYS_CONSENT: Randomization Date (Derived to days since study consent date)

  • RNDMDT_DAYS_T0: Randomization Date (Derived to days since study start date [A4: Ranomization date | LEARN: Baseline registry exam date])

  • GDSSEVBL: Geriatric Depression Scale Score > 5

  • SUBJCOMPTR: Subj Completer Set - TR Phase

  • TRTENDT_DAYS_CONSENT: Treatment End Date (Derived to days since study consent date)

  • TRTENDT_DAYS_T0: Treatment End Date (Derived to days since study start date [A4: Ranomization date | LEARN: Baseline registry exam date])

  • TRTSTDT_DAYS_CONSENT: Treatment Start Date (Derived to days since study consent date)

  • TRTSTDT_DAYS_T0: Treatment Start Date (Derived to days since study start date [A4: Ranomization date | LEARN: Baseline registry exam date])

  • TRTESDT_DAYS_CONSENT: Treatment Escalation Date: Date of the first visit participant started high dose (800 mg or 1600 mg) (Derived to days since study consent date)

  • TRTESDT_DAYS_T0: Treatment Escalation Date: Date of the first visit participant started high dose (800 mg or 1600 mg) (Derived to days since study start date [A4: Ranomization date | LEARN: Baseline registry exam date])

  • TRTESVIS: Treatment Escalation Visit: First visit participant started high dose (800 mg or 1600 mg)

  • HGTCMBL: Height in Cm at Baseline

  • WGTKGBL: Weight in Kg at Baseline

  • BMIBL: body mass index (weight (kg) / [height (m)]^2)

  • ALCHLBL: Current Alcohol Consumer at Baseline

  • CFBL: Current Caffeine User at Baseline

  • TBBL: Current Tobacco User at Baseline

  • COGDSSTTSV1: DSST Total Score at Visit 1

  • COGDSSTTSV6: DSST Total Score at Visit 6

  • COGLMDRTSV1: LM Delayed Recall Total Score at Visit 1

  • COGLMDRTSV6: LM Delayed Recall Total Score at Visit 6

  • COGTOTRECSV1: Total Recall Score at Visit 1

  • COGTOTRECSV6: Total Recall Score at Visit 6

  • MMSETSV1: MMSE Total Score at Visit 1

  • MMSETSV6: MMSE Total Score at Visit 6

  • PACCV6: PACC Total Score at Visit 6

  • APOEGN: APOE4 genotype (ε2/ε4, ε3/ε4, ε4/ε4, no ε4)

  • APOEGNPRSNFLG: APOE4 carrier status (carrier [ε2/ε4, ε3/ε4, ε4/ε4], noncarrier [ε3/ε3, ε2/ε2,ε3/ε2])

  • AAPOEGNPRSNFLG: APOE4 carrier status used for analysis. If APOEGNPRSNFLG is missing, carrier status is assumed to be noncarrier as in the randomization plan.

  • SUVRCER: Amyloid PET composite SUVR

  • AMYLCENT: Amyloid PET centiloids. AMYLCENT = 183.07 x SUVRCER – 177.26.

  • SUBJITTTR: Subj Intent to Treat Set - TR Phase

  • MITTFL: Modified Intent-to-Treat Flag

  • SUBJSAFTR: Safety Population Flag

  • PCCPFL: Placebo-Controlled Completers Population Flag

  • PRTVIIE: Protocol Violation - Eligibility Criteria Flag

  • PRTVIMAS: Protocol Violation - Missed ADCS-PACC Flag

  • CON3FL: Protocol Violation - Missed Consecutive Infusions

  • PRTVITMS: Protocol Violation - Missed Infusions

  • PPTRTDUR: Treatment Duration >240wk for Completers Flag

  • SUBJPPSTR: Subj Per Protocol Set - TR Phase

  • LEARNFL: LEARN Participant Flag

  • TAUPETFL: Tau PET (Flortaucipir) Participant Flag

  • FRAMINGHAM: Framingham Risk Score

  • RESCREENFL: Rescreened Participant Flag

  • PREVBID: Previous BID if previously screened

Examples

if (FALSE) { # \dontrun{
browseVignettes('A4LEARN')
} # }