ATRI derived analysis dataset.
Usage
data(ADQS)Details
SUBSTUDY: NA
BID: NA
VISITCD: Visit Code
VISIT: Visit
AVISIT: Analysis Visit
EPOCH: Epoch
QSSEQ: Sequence Number given to ensure uniqueness of subject records within a domain. May be any valid number.
QSTESTCD: Topic variable for QS. Short name for the value in QSTEST, which can be used as a column name when converting the dataset from a vertical format to a horizontal format. The value in QSTESTCD cannot be longer than 8 characters, nor can it start with a number (e.g.”1TEST”). QSTESTCD cannot contain characters other than letters, numbers, or underscores. See QS Terminology Spreadsheet for specific text for QSTESTCD. Examples: ADCCMD01, BPR0103
QSTEST: Verbatim name of the question or group of questions used to obtain the measurement or finding. The value in QSTEST cannot be longer than 40 characters. See QS Terminology Spreadsheet for specific text for QSTEST. Example: Fist, BPR01 - Emotional Withdrawal
QSCAT: Used to define a category of related records that will be meaningful to the Reviewer. See QS Terminology Spreadsheet for specific text for QSCAT. Examples: ADAS-COG, MDS-UPDRS.
QSVERSION: Test version administered.
QSLANG: Questionnaire language.
QSSTRESN: Used for continuous or numeric findings in standard format; copied in numeric format from QSSTRESC. QSSTRESN should store all numeric results or findings.
QSBLRES: QS Baseline Score
QSCHANGE: QS Change from Baseline
QSBLSD: QS Baseline Standard Deviation
QSBLFL: Indicator used to identify a baseline value. The value should be “Y” or null.
QSDTC_DAYS_CONSENT: Date of questionnaire. registry.EXAMDATE (Derived to days since study consent date)
QSDTC_DAYS_T0: Date of questionnaire. registry.EXAMDATE (Derived to days since study start date [A4: Ranomization date | LEARN: Baseline registry exam date])
QSADTC_DAYS_CONSENT: Analysis date of questionnaire. registry.EXAMDATE, if it exists, otherwise manually reviewed missing_pacc_dates_verify.EXAMDATE.verify (Derived to days since study consent date)
QSADTC_DAYS_T0: Analysis date of questionnaire. registry.EXAMDATE, if it exists, otherwise manually reviewed missing_pacc_dates_verify.EXAMDATE.verify (Derived to days since study start date [A4: Ranomization date | LEARN: Baseline registry exam date])
QSDY: Study Day of Finding
ADURW: Study Week of Finding
ASEQMMRM: Sequence for MMRM, mapped using AVISIT (012->1...066->10)
ASEQNCS: Sequence for NCS, mapped using AVISIT (006->1...066->11) for participant without missing AVISIT, and use Visit Number for those with missing AVISIT (max 11 visits, and visit code 066 is always visit 11)
ANL01FL: Y if data should be included in NCS.
ANL02FL: Y if data should be included in MMRM.
TX: Random treatment assigment.
AGEYR: Age in years at Consent
MARITAL: Marital Status
SEX: Sex
RACE: Race
EDCCNTU: Years of education
ETHNIC: Ethnicity
WRKRET: Participant Retirement Status
TESTLNG: Language to be used for testing
SAMELNG: Testing and Primary Lang are the same
RESIDENCE: Type of Residence
DISCDTC_DAYS_CONSENT: Subject Discontinuation Date Character (Derived to days since study consent date)
DISCDTC_DAYS_T0: Subject Discontinuation Date Character (Derived to days since study start date [A4: Ranomization date | LEARN: Baseline registry exam date])
ENRLDT_DAYS_CONSENT: Enrollment Date (Derived to days since study consent date)
ENRLDT_DAYS_T0: Enrollment Date (Derived to days since study start date [A4: Ranomization date | LEARN: Baseline registry exam date])
RNDMDT_DAYS_CONSENT: Randomization Date (Derived to days since study consent date)
RNDMDT_DAYS_T0: Randomization Date (Derived to days since study start date [A4: Ranomization date | LEARN: Baseline registry exam date])
GDSSEVBL: Geriatric Depression Scale Score > 5
SUBJCOMPTR: Subj Completer Set - TR Phase
TRTENDT_DAYS_CONSENT: Treatment End Date (Derived to days since study consent date)
TRTENDT_DAYS_T0: Treatment End Date (Derived to days since study start date [A4: Ranomization date | LEARN: Baseline registry exam date])
TRTSTDT_DAYS_CONSENT: Treatment Start Date (Derived to days since study consent date)
TRTSTDT_DAYS_T0: Treatment Start Date (Derived to days since study start date [A4: Ranomization date | LEARN: Baseline registry exam date])
HGTCMBL: Height in Cm at Baseline
WGTKGBL: Weight in Kg at Baseline
BMIBL: body mass index (weight (kg) / [height (m)]^2)
ALCHLBL: Current Alcohol Consumer at Baseline
CFBL: Current Caffeine User at Baseline
TBBL: Current Tobacco User at Baseline
COGDSSTTSV1: DSST Total Score at Visit 1
COGDSSTTSV6: DSST Total Score at Visit 6
COGLMDRTSV1: LM Delayed Recall Total Score at Visit 1
COGLMDRTSV6: LM Delayed Recall Total Score at Visit 6
COGTOTRECSV1: Total Recall Score at Visit 1
COGTOTRECSV6: Total Recall Score at Visit 6
MMSETSV1: MMSE Total Score at Visit 1
MMSETSV6: MMSE Total Score at Visit 6
PACCV6: PACC Total Score at Visit 6
APOEGN: APOE4 genotype (ε2/ε4, ε3/ε4, ε4/ε4, no ε4)
APOEGNPRSNFLG: APOE4 carrier status (carrier [ε2/ε4, ε3/ε4, ε4/ε4], noncarrier [ε3/ε3, ε2/ε2,ε3/ε2])
AAPOEGNPRSNFLG: APOE4 carrier status used for analysis. If APOEGNPRSNFLG is missing, carrier status is assumed to be noncarrier as in the randomization plan.
SUVRCER: Amyloid PET composite SUVR
AMYLCENT: Amyloid PET centiloids. AMYLCENT = 183.07 x SUVRCER – 177.26.
SUBJITTTR: Subj Intent to Treat Set - TR Phase
MITTFL: Modified Intent-to-Treat Flag
SUBJSAFTR: Safety Population Flag
PCCPFL: Placebo-Controlled Completers Population Flag
PRTVIIE: Protocol Violation - Eligibility Criteria Flag
PRTVIMAS: Protocol Violation - Missed ADCS-PACC Flag
CON3FL: Protocol Violation - Missed Consecutive Infusions
PRTVITMS: Protocol Violation - Missed Infusions
PPTRTDUR: Treatment Duration >240wk for Completers Flag
SUBJPPSTR: Subj Per Protocol Set - TR Phase
TAUPETFL: Tau PET (Flortaucipir) and mITT Participant Flag
Examples
if (FALSE) { # \dontrun{
browseVignettes('A4LEARN')
} # }